The Synthesis Cycle to be Used

Determining the cost of a modified oligo begins with selecting the scale of the synthesis, then determining the appropriate per residue charges.

  • A normal DNA per-residue charge is used for the modified residues unless those modifiers are RNA or 2'-O- methyl RNA.

Please see our price schedule and Oligo Cost Calculator for charges.

Most of our specialty reagents are ordered from Glen Research. Glen offers only 0.2 micromole and 1.0 micromole columns for initiating syntheses with 3' modified residues.

Contact oligos@yale.edu for a quote.